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Methoxypolyethylene glycol succinate N-hydroxysuccinimide

SIGMA/85976 - 5,000, ≥90%

Synonym: Polyethylene glycol; mono-Methyl polyethylene glycol succinate N-succinimidyl ester; O-Methyl-O′-succinylpolyethylene glycol 5,000 N-succinimidyl ester; PEG-succinimidyl succinate

CAS Number: 78274-32-5
MDL Number: MFCD00131598
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-85976-250MG 250 mg
 $283.00
1/EA		 Add To Favorites
45-85976-1G 1 g
 $829.00
1/EA		 Add To Favorites

 

assay ≥90%
form powder
InChI 1S/C11H15NO7/c13-5-6-18-7-8(14)1-4-11(17)19-12-9(15)2-3-10(12)16/h13H,1-7H2
InChI key OVPTZXRXNNJKSJ-UHFFFAOYSA-N
Quality Level 100 
SMILES string N1(C(=O)CCC1=O)OC(=O)CCC(=O)COCCO
storage temp. −20°C
Application:

  • Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation. This study explores the use of Methoxypolyethylene glycol succinate N-hydroxysuccinimide (MPEG-S-NHS) for creating peptide-conjugated polymer micelles that are sensitive to matrix metalloproteinases-2/9. These micelles are designed for site-specific drug release and increased tumor targeting, showcasing a promising application in advanced drug delivery systems (Zhang X, Wang X, Zhong W, Ren X, Sha X, Fang X, 2016) [link] .
Other Notes: Shearwater Polymers product
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥90%
Storage Temp. −20°C
UNSPSC 12162002

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