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Spermine tetrahydrochloride

SIGMA/85610 - ≥99.0% (AT), powder or crystals

Synonym: N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride

CAS Number: 306-67-2
Empirical Formula (Hill Notation): C10H26N4 · 4HCl
Molecular Weight: 348.18
EC Number: 206-189-8
MDL Number: MFCD00012914
Linear Formula: C10H26N4 · 4HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-85610-5G 5 g
$300.00
1/EA
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45-85610-25G 25 g
$1080.00
1/EA
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assay ≥99.0% (AT)
biological source microbial
  synthetic
form powder or crystals
InChI 1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChI key XLDKUDAXZWHPFH-UHFFFAOYSA-N
mp 310-311 °C (dec.) (lit.)
Quality Level 300 
SMILES string Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
solubility H2O: 0.1 g/mL, clear
storage temp. room temp
Application: Used to precipitate DNA from low salt aqueous buffers.
Biochem/physiol Actions: Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Biochem/physiol Actions: Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Biochem/physiol Actions: Mixed NMDA agonist/antagonist at the polyamine site. Role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Purity ≥99.0% (AT)
mp 310-311 °C (dec.) (lit.)
Storage Temp. room temp
UNSPSC 12352200

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