Peptidoglycan from Staphylococcus aureus
SIGMA/77140 - cell wall component
Synonym: Peptidoglycan from S. aureus
MDL Number: MFCD00212486
Product Type: Chemical
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| form | lyophilized powder |
| Quality Level | 100  |
| solubility | soluble, hazy to turbid, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | Peptidoglycan from Staphylococcus aureus has been used: • for the stimulation of lymphocytes: peptidoglycan activates the toll-like receptor 2 (TLR2), present in mammalian cells. It works as an antagonist of Poly (I:C) • for g-type lysozyme stimulation by intraperitoneally inoculating it into sole specimens • in phosphate buffer saline and injected into Labeo rohita fingerlings, to study its effect on nucleotide-binding oligomerization domain-2 (NOD-2) gene expression |
| Biochem/physiol Actions: | The cell wall of gram positive bacteria is largely made up of peptidoglycan. It is composed of polysaccharide chains interlinked by peptide bridges. This peptidoglycan gives a certain rigidity to the cell wall and gives the cell mechanical strength. It is a surface molecule which is known to stimulate immune reactions including cytokine production to fever. |
| Other Notes: | Major component of the cell wall in gram positive organisms. Consists of a glycan backbone with alternating β 1-4 linked residues of N-acetyl-D-glucosamine and muramic acid. The immunological activities of bacterial peptidoglycans; Peptidoglycan types of bacterial cell walls and their taxonomic implications; Antibody response to peptidoglycan during staphylococcal infections. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352201 |