Myricetin
SIGMA/70050 - ≥96.0% (HPLC)
Synonym: 3,3′,4′,5,5′,7-Hexahydroxyflavone; Cannabiscetin; Myricetol
CAS Number: 529-44-2
Empirical Formula (Hill Notation): C15H10O8
Molecular Weight: 318.24
EC Number: 208-463-2
MDL Number: MFCD00006827
Linear Formula: C15H10O8
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥96.0% (HPLC) |
| form | powder |
| InChI | 1S/C15H10O8/c16-6-3-7(17) |
| InChI key | IKMDFBPHZNJCSN-UHFFFAOYSA |
| mp | ≥300 °C |
| >300 °C (lit.) | |
| Quality Level | 200  |
| SMILES string | Oc1cc(O)c2C(=O)C(O)=C(Oc2 |
| solubility | ethanol: 10 mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow |
| Application: | Myricetin has been used: • to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in rats • as a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP) • to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicans • as a reference standard for the quantification of phenolic compounds from Juniperus species |
| Biochem/physiol Actions: | Myricetin exerts anti-oxidant effects, and anti-inflammatory effects by regulating multiple signal pathways. It also displays anti-diabetic and hepatoprotective effects. Myricetin strongly inhibits yeast α-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase. It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy. Myricetin also has various nutraceuticals values and therapeutic effects. |
| General description: | Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥96.0% (HPLC) |
| mp | ≥300 °C; >300 °C (lit.) |
| UNSPSC | 12352202 |