Sodium iodoacetate
SIGMA/57858 - BioUltra, ≥99.5% (NT)
Synonym: Iodoacetic acid sodium salt
CAS Number: 305-53-3
Empirical Formula (Hill Notation): C2H2INaO2
Molecular Weight: 207.93
EC Number: 206-165-7
MDL Number: MFCD00002686
Linear Formula: ICH2COONa
Product Type: Chemical
| absorption | cut-off at 335 nm in methanol at 0.1 M |
| anion traces | chloride (Cl-): ≤100 mg/kg |
| sulfate (SO42-): ≤100 mg/kg | |
| assay | ≥99.5% (NT) |
| cation traces | Al: ≤5 mg/kg |
| As: ≤0.1 mg/kg | |
| Ba: ≤5 mg/kg | |
| Bi: ≤5 mg/kg | |
| Ca: ≤10 mg/kg | |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤500 mg/kg | |
| Li: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Mo: ≤5 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Sr: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| impurities | insoluble matter, passes filter test |
| ≤0.5% water | |
| InChI | 1S/C2H3IO2.Na/c3-1-2(4)5; |
| InChI key | AGDSCTQQXMDDCV-UHFFFAOYSA |
| mp | 208 °C (dec.) (lit.) |
| product line | BioUltra |
| Quality Level | 100  |
| SMILES string | [Na+].[O-]C(=O)CI |
| solubility | methanol: 0.1 M at 20 °C, clear, colorless |
| storage temp. | −20°C |
| Application: | Reagent for the modification of cysteine residues in proteins. |
| Application: | Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains. |
| Application: | Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease. |
| Other Notes: | Sulfhydryl reagent |
| Symbol |   GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H314 |
| Precautionary statements | P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 25-37/38-41 |
| Safety Statements | 26-39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 406.4 °F |
| Flash Point(C) | 208 °C |
| Purity | ≥99.5% (NT) |
| mp | 208 °C (dec.) (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352106 |