L-Histidine monohydrochloride monohydrate

SIGMA/53370 - ≥99.0% (AT)

Synonym: L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride

CAS Number: 5934-29-2
Empirical Formula (Hill Notation): C₆H₉N₃O₂ · HCl · H₂O
Molecular Weight: 209.63
MDL Number: MFCD00151027
Linear Formula: C₆H₉N₃O₂ · HCl · H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-53370-25G	25 g	$36.30 1/EA	Add To Favorites
45-53370-100G	100 g	$118.00 1/EA	Add To Favorites
45-53370-500G	500 g	$420.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

anion traces	sulfate (SO₄^2-): ≤100 mg/kg
assay	≥99.0% (AT)
cation traces	Ca: ≤10 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤5 mg/kg
	K: ≤50 mg/kg
	Mg: ≤5 mg/kg
	Mn: ≤5 mg/kg
	Na: ≤50 mg/kg
	NH₄⁺: ≤500 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤5 mg/kg
	Zn: ≤5 mg/kg
form	solid
impurities	≤0.3% foreign amino acids
InChI	1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI key	CMXXUDSWGMGYLZ-XRIGFGBMSA-N
mp	254 °C (dec.) (lit.)
optical activity	[α]20/D +9.5±0.5°, c = 5% in 5 M HCl
Quality Level	100
SMILES string	O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
solubility	H₂O: 1 g/10 mL, clear, colorless (hot)

Biochem/physiol Actions:	L-Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. This essential amino acid can be degraded to glutamate by histidiase, urocanase and imidazolonepropionase; it is also the precursor of histamine by action of histidine decarboxylase.
General description:	L-Histidine is a hydrophilic essential amino acid that has a basic sidechain containing an imidazole group.

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P264 - P280 - P305 + P351 + P338 - P337 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.0% (AT)
mp	254 °C (dec.) (lit.)
UNSPSC	12352209

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