L-Histidine dihydrochloride
SIGMA/53340 - ≥99.0% (AT)
Synonym: L-Histidine hydrochloride (1:2)
CAS Number: 6027-02-7
Empirical Formula (Hill Notation): C6H9N3O2 · 2HCl
Molecular Weight: 228.08
EC Number: 227-890-5
MDL Number: MFCD00066569
Linear Formula: C6H9N3O2 · 2HCl
Product Type: Chemical
| anion traces | sulfate (SO42-): ≤50 mg/kg |
| assay | ≥99.0% (AT) |
| cation traces | As: ≤0.1 mg/kg |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| NH4+: ≤500 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| color | white |
| form | powder or crystals |
| ign. residue | ≤0.1% (as SO4) |
| InChI | 1S/C6H9N3O2.2ClH/c7-5(6(1 |
| InChI key | XEJCDBUNISUVGZ-XRIGFGBMSA |
| mp | 240-245 °C (dec.) |
| optical activity | [α]20/D +6.5±1°, c = 8% in H2O |
| Quality Level | 100 ![]() |
| SMILES string | Cl.Cl.N[C@@H](Cc1c[nH]cn1 |
| solubility | H2O: soluble |
| saline: soluble |
| Biochem/physiol Actions: | L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty. |
| Biochem/physiol Actions: | L-Histidine is a positively charged imidazole-side chain containing α amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (AT) |
| mp | 240-245 °C (dec.) |
| UNSPSC | 12352209 |

