Guanidine hydrochloride
SIGMA/50940 - ≥99.0% (AT)
Synonym: Aminoformamidine hydrochloride; Aminomethanamidine hydrochloride; Guanidinium chloride
CAS Number: 50-01-1
Empirical Formula (Hill Notation): CH5N3 · HCl
Molecular Weight: 95.53
EC Number: 200-002-3
MDL Number: MFCD00013026
Linear Formula: NH2C(=NH)NH2 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 50940-500G
This image depicts SKU: 50940-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 50940-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 50940-1KG
This image depicts SKU: 50940-1KG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 50940-10G
This image depicts SKU: 50940-10G
| anion traces | sulfate (SO42-): ≤50 mg/kg |
| assay | ≥99.0% (AT) |
| cation traces | Ca: ≤20 mg/kg |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Na: ≤50 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| density | 1.3 g/cm3 (lit.) |
| form | solid |
| ign. residue | ≤0.1% (as SO4) |
| InChI | 1S/CH5N3.ClH/c2-1(3)4;/h( |
| InChI key | PJJJBBJSCAKJQF-UHFFFAOYSA |
| mp | 180-185 °C (lit.) |
| pH | (25 °C, 4.6 - 6/573 g/L) |
| Quality Level | 200  |
| SMILES string | Cl[H].NC(N)=N |
| solubility | H2O: 6 M at 20 °C, clear, colorless |
| Application: | Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 10 g in poly bottle |
| Packaging: | 100 g in glass bottle |
| Packaging: | 5 kg in poly drum |
| Packaging: | 500 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 + H332 - H315 - H319 |
| Precautionary statements | P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/38 |
| Safety Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (AT) |
| mp | 180-185 °C (lit.) |
| Density | 1.3 g/cm3 (lit.) |
| UNSPSC | 12352107 |