Fluorescein-5-thiosemicarbazide

SIGMA/46985 - suitable for fluorescence, ~80% (HPCE)

CAS Number: 76863-28-0
Empirical Formula (Hill Notation): C₂₁H₁₅N₃O₅S
Molecular Weight: 421.43
MDL Number: MFCD00155658
Linear Formula: C₂₁H₁₅N₃O₅S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-46985-100MG-F	100 mg	$393.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	~80% (HPCE)
fluorescence	λ_ex 492 nm; λ_em 516 nm in 0.1 M Tris pH 9.0
form	solid
InChI	1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
InChI key	MEUCHQDLZYLNQY-UHFFFAOYSA-N
Quality Level	100
SMILES string	NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
solubility	DMF: soluble
	H₂O: soluble
storage temp.	−20°C
suitability	suitable for fluorescence

Application:	Fluorescein-5-thiosemicarbazide can be used as a fluorescent labeling reagent to label: • Cell-surface functional groups (glycophorins) in the study of the effect of deoxygenation in the red blood cell membrane. • Saccharides applicable in polysaccharide imaging in live cells. • Chondroitin sulfate nanogels applicable in cell-specific drug delivery applications.
Features and Benefits:	Fluorescein-5-thiosemicarbazide has the following benefits - • It displays strong fluorescence property. • Shows an intrinsic reactivity of the thiosemicarbazide group towards the aldehyde group.
General description:	Fluorescein-5-thiosemicarbazide, also known as FTC, is a fluorescent probe. The FTSC fluorescent spectra is like FITC, a preferred fluorescent tag for proteomics. The fluorescence spectral properties of FTSC-labeled vesicles obtained by reductive amination are fully compatible with the argon laser of fluorescent instruments.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	~80% (HPCE)
Storage Temp.	−20°C
UNSPSC	12352125

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