Fluorescein isothiocyanate–dextran
SIGMA/46945 - average mol wt 70,000, (FITC:Glucose = 1:250)
Synonym: FITC-Dextran 70; FITC–Dextran
CAS Number: 60842-46-8
MDL Number: MFCD00131092
Product Type: Chemical
| application(s) | cell analysis |
| biological source | synthetic |
| composition | (FITC:Glucose = 1:250) |
| conjugate | FITC conjugate |
| extent of labeling | ~0.004 mol/mol FITC glucose |
| fluorescence | λex 492 nm; λem 518 nm in ethanol |
| form | powder |
| mol wt | average mol wt 70,000 |
| Quality Level | 100  |
| solubility | H2O: 50 mg/mL, hazy, orange to very deep orange |
| storage temp. | 2-8°C |
| Application: | Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. |
| Application: | Fluorescein isothiocyanate–dextran (FITC-Dextran 70) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-Dextran 70 may be used to study the capacity, selectivity and efficiency of encapsulation and release by drug delivery vehicles. |
| Other Notes: | Internalisation of FITC and FITC-dextran by suspension cultured plant cells; In the study of fluid pinocytosis in leukocytes |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352201 |