p53 (DO7) Mouse Monoclonal Antibody
SIGMA/453M-9
Product Type: Chemical
Immunohistochemistry p53 (DO7) on colon carcinoma
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | DO7, monoclonal |
| conjugate | unconjugated |
| control | colon carcinoma |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| isotype | IgG2bκ |
| manufacturer/tradename | Cell Marque® |
| packaging | bottle of 1.0 mL predilute (453M-97) |
| bottle of 7.0 mL predilute (453M-98) | |
| vial of 0.1 mL concentrate (453M-94) | |
| vial of 0.5 mL concentrate (453M-95) | |
| vial of 1.0 mL concentrate (453M-96) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| visualization | nuclear |
| Analysis Note: |
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| General description: | Anti-p53 tumor suppressor protein recognizes a 53 kDa hosphoprotein, identified as a p53 suppressor gene product. It reacts with the mutant as well as wild form of p53. Positive nuclear staining with this antibody has been shown to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. | ||||
| Legal Information: | Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany | ||||
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Other Notes: | p53 Positive Control Slides, Product No. 453S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
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| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |