FOXA1 (2F83) Mouse Monoclonal Antibody
SIGMA/405M-1
Product Type: Chemical
Immunohistochemistry FOXA1 (2F83) on breast carcinoma
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2F83, monoclonal |
| conjugate | unconjugated |
| control | breast carcinoma |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| isotype | IgG1κ |
| manufacturer/tradename | Cell Marque® |
| packaging | bottle of 1.0 mL predilute (405M-17) |
| bottle of 7.0 mL predilute (405M-18) | |
| vial of 0.1 mL concentrate (405M-14) | |
| vial of 0.5 mL concentrate (405M-15) | |
| vial of 1.0 mL concentrate (405M-16) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| visualization | nuclear |
| Analysis Note: |
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| General description: | Forkhead box A1 (FOXA1), also known as hepatocyte nuclear factor 3 alpha(HNF3a), is a transcription factor expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. It has been reported to co-express with ER in breast carcinoma, predominantly in luminal subtype A. FOXA1 expression has been identified in 42% - 75% of invasive carcinoma of the breast. Of the FOXA1-positive breast invasive carcinomas, 83% were comprised of ER+/PR+/Her2+ luminal A subtype. The results indicate that anti-FOXA1 is useful in the sub-classification of breast carcinoma. | ||||
| Legal Information: | Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany | ||||
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Other Notes: | FOXA1 Positive Control Slides, Product No. 405S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
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| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |