C4d (SP91) Rabbit Monoclonal Antibody
SIGMA/404R-1
Product Type: Chemical
Immunohistochemistry C4d (SP91) on kidney (rejection)
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | SP91, monoclonal |
| conjugate | unconjugated |
| control | lymph node, tonsil |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| isotype | IgG |
| manufacturer/tradename | Cell Marque® |
| packaging | bottle of 1.0 mL predilute (404R-17) |
| bottle of 7.0 mL predilute (404R-18) | |
| vial of 0.1 mL concentrate (404R-14) | |
| vial of 0.5 mL concentrate (404R-15) | |
| vial of 1.0 mL concentrate (404R-16) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 |
| visualization | cytoplasmic, membranous |
| Analysis Note: |
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| General description: | Acute humoral rejection is mediated by antibodies to the donor endothelium that activates the classical complement pathway. This leads to a number of split products of complement proteins. C4d is a fragment of C4 complement released during activation of the classic complement pathway by the antigen-antibody complex. C4d deposits in peritubular capillaries and is regarded as an indirect sign of an antibody response. C4d can be a useful tool for indicating acute renal allograft rejection. | ||||
| Legal Information: | Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany | ||||
| Other Notes: | C4d Positive Control Slides, Product No. 404S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
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| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |