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Galangin

SIGMA/282200 - autophagy inducing flavonoid

Synonym: 3,5,7-Trihydroxyflavone; Norizalpinin

CAS Number: 548-83-4
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
EC Number: 208-960-4
MDL Number: MFCD00006833
Linear Formula: C15H10O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-282200-25MG 25 mg
 $0.00
1/EA
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45-282200-100MG 100 mg
 $595.00
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assay ≥95% (HPLC)
color yellow
form powder
InChI 1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
InChI key VCCRNZQBSJXYJD-UHFFFAOYSA-N
mp 214-215 °C (lit.)
Quality Level 100 
SMILES string Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccccc3
Application: Galangin has been used:
• as a test drug to test its ameliorative effect in a rodent model of cisplatin-induced nephrotoxicity
• to test its effect on the differentiation of 3T3-L1 preadipocyte cells into adipocytes
• as an internal standard in nuclear magnetic resonance spectroscopy and mass spectroscopy
Biochem/physiol Actions: Galangin exhibits antioxidant, anti-apoptotic, anti-inflammatory and anti-obesity properties. In addition, it also possesses anti-genotoxic activity against environmental and dietary carcinogens. Galangin inhibits cancer growth by hindering cancer cell proliferation, induction of apoptosis and autophagy and inhibition of metastasis. Galangin also has an ability to inhibit CYP1A1 (Cytochrome P450, family 1, member A1) activity.
General description: Galangin is a flavonoid isolated from members of the Zingiberaceae family, which are mainly used for herbal medicines.
Packaging: 25, 100 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
mp 214-215 °C (lit.)
UNSPSC 41116107

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