Glucagon Rabbit Polyclonal Antibody
SIGMA/259A-1
Product Type: Chemical
Immunohistochemistry Glucagon (polyclonal) on pancreas tissue
| antibody form | Ig fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| control | pancreas |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| manufacturer/tradename | Cell Marque® |
| packaging | bottle of 1.0 mL predilute (259A-17) |
| bottle of 7.0 mL predilute (259A-18) | |
| vial of 0.1 mL concentrate (259A-14) | |
| vial of 0.5 mL concentrate (259A-15) | |
| vial of 1.0 mL concentrate (259A-16) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| visualization | cytoplasmic |
| Analysis Note: |
|
||||
| General description: | The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon. Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.Immunohistochemically, the two types of glucagonoma are reactive to the glucagon antibody, though occasionally only weakly. | ||||
| Legal Information: | Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany | ||||
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Other Notes: | Glucagon (polyclonal) Positive Control Slides, Product No. 259S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
||||
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |