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5(6)-Carboxytetramethylrhodamine

SIGMA/21953 - BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

CAS Number: 98181-63-6
Empirical Formula (Hill Notation): C25H22N2O5
Molecular Weight: 430.45
MDL Number: MFCD16661194
Linear Formula: C25H22N2O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-21953-100MG-F 100 mg
$286.00
1/EA
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45-21953-500MG-F 500 mg
$950.00
1/EA
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assay ≥85% (sum of isomers, HPCE)
fluorescence λex 543 nm; λem 572 nm in methanol
form solid
InChI 1S/2C25H22N2O5/c1-26(2)15-6-9-19-21(12-15)31-22-13-16(27(3)4)7-10-20(22)25(19)18-8-5-14(23(28)29)11-17(18)24(30)32-25;1-26(2)15-6-9-18-21(12-15)31-22-13-16(27(3)4)7-10-19(22)25(18)20-11-14(23(28)29)5-8-17(20)24(30)32-25/h2*5-13H,1-4H3,(H,28,29)
InChI key LBUFYZITRTUEFI-UHFFFAOYSA-N
mp ≥300 °C (lit.)
product line BioReagent
Quality Level 100 
SMILES string CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(O)=O)N(C)C)c1.CN(C)c6ccc7c(Oc8cc(ccc8C79OC(=O)c%10ccc(cc9%10)C(O)=O)N(C)C)c6
solubility DMF: soluble
  DMSO: soluble
suitability suitable for fluorescence
Application: 5(6)-Carboxytetramethylrhodamine (TAMRA, TMR) may be used as a fluorescence probe to study the distribution of molecules such as cell-penetrating peptides (CPPs) and as fluorescence partner in applications such as two-dimensional fluorescence intensity distribution analysis (2D-FIDA), luminescence resonance energy transfer (LRET) and fluorescence resonance energy transfer (FRET).
Application: Reacts with primary and secondary amine groups on proteins, nucleic acids and other biomolecules.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥85% (sum of isomers, HPCE)
mp ≥300 °C (lit.)
UNSPSC 12352116

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