CD8 (SP16) Rabbit Monoclonal Antibody
SIGMA/108R-1
Product Type: Chemical
Immunohistochemistry CD8 (SP16) on hepatosplenic T-cell lymphoma
| antibody form | culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | SP16, monoclonal |
| conjugate | unconjugated |
| control | tonsil |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| isotype | IgG1 |
| manufacturer/tradename | Cell Marque™ |
| packaging | bottle of 1.0 mL predilute (108R-17) |
| bottle of 7.0 mL predilute (108R-18) | |
| vial of 0.1 mL concentrate (108R-14) | |
| vial of 0.5 mL concentrate (108R-15) | |
| vial of 1.0 mL concentrate (108R-16) | |
| Quality Level | 100  |
| 500 |
|
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | 2-8°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| visualization | membranous |
| General description: | Anti-CD8 is a T-cell marker for the detection of cytotoxic/suppressor lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody, along with other markers, can be used to distinguish between reactive and neoplastic T-cells. Expression of both CD4 (+) and CD8 (+), or lack of expression of both markers in a lymphoid population would be evidence for lymphoma. Although most T-cell lymphoma/leukemias can be either CD8+ or CD8-, CD8 positivity is a factor against Mycosis Fungoides as this entity is negative for CD8. Rarely does anti-CD8 label non-hematolymphoid neoplasms. |
| Legal Information: | Cell Marque is a trademark of Sigma-Aldrich Co. LLC |
| Linkage: | CD8 Positive Control Slides, Product No. 108S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). |
| Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com |
| Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Preparation Note: | Download the IFU specific to your product lot and format  Note: This requires a keycode which can be found on your packaging or product label. |
| RIDADR | NONH for all modes of transport |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |