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(R)-(+)-α-Lipoic acid

SIGMA/07039 - ≥98.0% (HPLC)

Synonym: (R)-(+)-1,2-Dithiolane-3-pentanoic acid; (R)-6,8-Dithiooctanoic acid; (R)-6,8-Thioctic acid

CAS Number: 1200-22-2
Empirical Formula (Hill Notation): C8H14O2S2
Molecular Weight: 206.33
MDL Number: MFCD01631142
Linear Formula: C8H14O2S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-07039-10MG 10 mg
 $0.00
1/EA
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45-07039-50MG 50 mg
 $0.00
1/EA
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45-07039-500MG 500 mg
 $1120.00
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assay ≥98.0% (HPLC)
InChI 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key AGBQKNBQESQNJD-SSDOTTSWSA-N
mp 48-52 °C (lit.)
optical purity enantiomeric excess: ≥98.0% (HPLC)
Quality Level 100 
  200 
SMILES string OC(=O)CCCC[C@@H]1CCSS1
storage temp. −20°C
Analysis Note: identity confirmed by LC-MS
Biochem/physiol Actions: (R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.0% (HPLC)
mp 48-52 °C (lit.)
Storage Temp. −20°C
UNSPSC 12352202

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