Synonym: (R)-(+)-1,2-Dithiolane-3-pentanoic acid; (R)-6,8-Dithiooctanoic acid; (R)-6,8-Thioctic acid
CAS Number: 1200-22-2
Empirical Formula (Hill Notation): C8H14O2S2
Molecular Weight: 206.33
MDL Number: MFCD01631142
Linear Formula: C8H14O2S2
Product Type: Chemical
| assay |
≥98.0% (HPLC) |
| InChI |
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1 |
| InChI key |
AGBQKNBQESQNJD-SSDOTTSWSA-N |
| mp |
48-52 °C (lit.) |
| optical purity |
enantiomeric excess: ≥98.0% (HPLC) |
| Quality Level |
100  |
| |
200 |
| SMILES string |
OC(=O)CCCC[C@@H]1CCSS1 |
| storage temp. |
−20°C |
| Analysis Note: |
identity confirmed by LC-MS |
| Biochem/physiol Actions: |
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease. |
| Packaging: |
Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98.0% (HPLC) |
| mp |
48-52 °C (lit.) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352202 |
