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2-Aminoacridone

SIGMA/06627 - BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

Synonym: 2-Amino-9(10H)-acridinone; 2-amino-10H-acridin-9-one; AMAC

CAS Number: 27918-14-5
Empirical Formula (Hill Notation): C13H10N2O
Molecular Weight: 210.23
MDL Number: MFCD00037397
Linear Formula: C13H10N2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-06627-25MG 25 mg
 $145.00
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45-06627-100MG 100 mg
 $413.00
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assay ≥98.0% (HPLC)
fluorescence λex 420 nm; λem 542 nm in 0.1 M Tris pH 8.0
InChI 1S/C13H10N2O/c14-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)15-12/h1-7H,14H2,(H,15,16)
InChI key PIGCSKVALLVWKU-UHFFFAOYSA-N
product line BioReagent
Quality Level 100 
SMILES string Nc1ccc2Nc3ccccc3C(=O)c2c1
solubility DMF: soluble
  DMSO: soluble
suitability suitable for fluorescence
Application: 2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate and is reduced to a stable amine derivative by sodium borohydride (NaBH4). Picomolar levels of glycan compounds can be detected using this fluorophore. The resulting derivatzed compounds can be separated by reverse-phase HPLC and detected by positive-ion electrospray MS . An intense fluorescent, hydrophobic probe that is stable over a wide pH range is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides . The λ excitation and λ emission are 425 nm and 532 nm, respectively.
Application: Fluorescent label for glycans and saccharides.
Application: Fluorescent label for glycans and saccharides. The analysis of fluorophore-labeled glycans by high-resolution polyacrylamide gel electrophoresis.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
Purity ≥98.0% (HPLC)
UNSPSC 12352108

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