L-Alanyl-L-1-aminoethylphosphonic acid
SIGMA/05260 - ≥95% (HPLC)
Synonym: (S)-Alanyl-(R)
CAS Number: 60668-24-8
Empirical Formula (Hill Notation): C5H13N2O4P
Molecular Weight: 196.14
EC Number: 262-362-8
MDL Number: MFCD01569244
Linear Formula: C5H13N2O4P
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| assay | ≥95% (HPLC) |
| color | white |
| form | powder |
| InChI | 1S/C5H13N2O4P/c1-3(6)5(8) |
| InChI key | BHAYDBSYOBONRV-IUYQGCFVSA |
| mode of action | cell wall synthesis | interferes |
| enzyme | inhibits | |
| optical activity | [α]20/D −45±2°, c = 1% in H2O |
| Quality Level | 200  |
| SMILES string | C[C@H](N)C(=O)N[C@@H](C)P |
| storage temp. | 2-8°C |
| Application: | Alaphosphin is used as a selection agent for isolation of Salmonella and as a dipeptide mimetic antibacterial agent. |
| Biochem/physiol Actions: | Alaphosphin is an antibacterial phosphonopeptide which mimics the terminal dipeptide moiety (D-Ala-D-Ala) of bacterial cell wall peptidoglycan . It metabolizes aminophosphonic acid which inhibits alanine racemase and uridine 5-diphosphate-N-acetylmuramoylalanine synthetase. |
| Biochem/physiol Actions: | Alaphosphin is used as a selection agent for isolation of Salmonella and as a dipeptide mimetic antibacterial agent. It metabolizes aminophosphonic acid which inhibits alanine racemase and uridine 5-diphosphate-N-acetylmuramoylalanine synthetase. |
| General description: | Chemical structure: amino acid derivatives |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Moisture sensitive. Keep in a dry place. |
| Packaging: | 250MG |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 51101500 |