Tioconazole
SIGMA/03907 - 97%
Synonym: 1-
CAS Number: 65899-73-2
Empirical Formula (Hill Notation): C16H13Cl3N2OS
Molecular Weight: 387.71
EC Number: 265-973-8
MDL Number: MFCD00057276
Linear Formula: C16H13Cl3N2OS
Product Type: Chemical
antibiotic activity spectrum | fungi |
yeast | |
assay | ≥96.5% (HPLC) |
96.5-103.5% (NT) | |
97% | |
color | white to off-white |
form | powder |
InChI | 1S/C16H13Cl3N2OS/c17-12-1 |
InChI key | QXHHHPZILQDDPS-UHFFFAOYSA |
mode of action | cell membrane | interferes |
Quality Level | 100 |
SMILES string | Clc1ccc(C(Cn2ccnc2)OCc3cc |
Application: | Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo. |
Biochem/physiol Actions: | Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP. |
General description: | Chemical structure: pyrimidine |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. |
Other Notes: | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 03907.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
Packaging: | 10G |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥96.5% (HPLC); 96.5-103.5% (NT); 97% |
UNSPSC | 51101500 |