Adenosine 5′-monophosphate disodium salt

SIGMA/01930 - ≥99.0% (HPLC)

Synonym: 5′-AMP-Na₂

CAS Number: 4578-31-8
Empirical Formula (Hill Notation): C₁₀H₁₂N₅Na₂O₇P
Molecular Weight: 391.18
EC Number: 224-961-2
MDL Number: MFCD00065023
Linear Formula: C₁₀H₁₂N₅Na₂O₇P
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-01930-5G	5 g	$110.00 1/EA		Add To Favorites
45-01930-25G	25 g	$434.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99.0% (HPLC)
biological source	microbial (Candida utilis)
	synthetic
form	powder
impurities	≤26% water
InChI	1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChI key	QGXLVXZRPRRCRP-IDIVVRGQSA-L
optical activity	[α]20/D −43±2°, c = 1% in 0.5 M Na₂HPO₄ (dry matter)
Quality Level	100
SMILES string	[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O

Application:	Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase (EC 2.7.1.114), AMP deaminase (EC 3.5.4.6) and 5′-nucleotidase (EC 3.1.3.5).
Application:	Adenosine 5′-monophosphate disodium salt has been used: • as a dissolved organic phosphorus (DOP) compound to study its rate of hydrolysis in Escherichia coli lysates • to induce calcium responses in Fura2-loaded osteoblast (C2-OB)as a nucleotide metabolite in the medium for the isolation, culture, and identification of glioma stem cells (GSCs)
Biochem/physiol Actions:	Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase (EC 2.7.1.114), AMP deaminase (EC 3.5.4.6), and 5′-nucleotidase (EC 3.1.3.5).

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.0% (HPLC)
UNSPSC	41106305

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