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Ruthenium Red

SIGMA/00541 - for microscopy, 85.0-115.0% (calc. on dry basis, AT)

Synonym: Ammoniated ruthenium oxychloride

CAS Number: 11103-72-3
Empirical Formula (Hill Notation): H42Cl6N14O2Ru3
Molecular Weight: 786.35
MDL Number: MFCD00011479
Linear Formula: [(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-00541-1G 1 g
$255.00
1/EA
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45-00541-5G 5 g
$858.00
1/EA
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εmax ≥150 at 529-539 nm
application(s) diagnostic assay manufacturing
hematology
histology
assay 85.0-115.0% (calc. on dry basis, AT)
form powder
grade for microscopy
impurities ~5% water
InChI 1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
InChI key ZXYSDUPLHOJIOR-UHFFFAOYSA-H
Quality Level 100 
SMILES string N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]
solubility water: 10 mg/mL, clear to turbid
storage temp. room temp
Application: Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.
Application: Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx.
Biochem/physiol Actions: Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels.
General description: Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 85.0-115.0% (calc. on dry basis, AT)
Storage Temp. room temp
Colour Index Number 77800
UNSPSC 12352200

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