Acacetin
SIGMA/00017 - ≥97.0% (HPLC)
Synonym: 4′-Methylapigenin; 5,7-Dihydroxy-4′-methoxyflavone; Apigenin 4′-methyl ether; Buddleoflavonol; Linarigenin
CAS Number: 480-44-4
Empirical Formula (Hill Notation): C16H12O5
Molecular Weight: 284.26
EC Number: 207-552-3
MDL Number: MFCD00016936
Linear Formula: C16H12O5
Product Type: Chemical
| assay | ≥97.0% (HPLC) |
| form | powder or crystals |
| InChI | 1S/C16H12O5/c1-20-11-4-2- |
| InChI key | DANYIYRPLHHOCZ-UHFFFAOYSA |
| mp | 260-265 °C (lit.) |
| Quality Level | 100  |
| SMILES string | COc1ccc(cc1)C2=CC(=O)c3c( |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Acacetin has been noted to exhibit anti-peroxidative, anti-inflammatory, and anti-plasmodial properties. It has been posited to prevent the proliferation of Hep G2 cells, thereby causing cell apoptosis and subsequent anti-cancer action. It has antiarrhythmic properties and can be used in the treatment of Atrial fibrillation. |
| Biochem/physiol Actions: | Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine. It has been recognized as an antiproliferative agent on cancer cell lines by inducing apoptosis and blocking cell cycle progression in the G1 phase. |
| General description: | Acacetin belongs to the category of naturally occurring plant pigments called flavonoids found in vascular plants. It was first reported to be extracted from the leaves of Robinia pseuducacia. It has been used as an active component of traditional Chinese medicine Xuelianhua. |
| Other Notes: | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 00017.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97.0% (HPLC) |
| mp | 260-265 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |