Tetrahydrofuran
SIGALD/34865 - inhibitor-free, suitable for HPLC, ≥99.9%
Synonym: THF; Butylene oxide; Oxolane; Tetramethylene oxide
CAS Number: 109-99-9
Empirical Formula (Hill Notation): C4H8O
Molecular Weight: 72.11
EC Number: 203-726-8
MDL Number: MFCD00005356
Linear Formula: C4H8O
Product Type: Chemical
| absorption | ≤0.0044 at 315 nm |
| ≤0.005 at 350 nm | |
| ≤0.005 at 400 nm | |
| ≤0.02 at 300 nm | |
| ≤0.046 at 275 nm | |
| ≤0.18 at 250 nm | |
| ≤0.26 at 245 nm | |
| ≤1.0 at 212 nm | |
| application(s) | food and beverages |
| assay | ≥99.9% |
| autoignition temp. | 610 °F |
| bp | 65-67 °C (lit.) |
| color | APHA: ≤10 |
| density | 0.889 g/mL at 25 °C (lit.) |
| evapn. residue | ≤0.0005% |
| expl. lim. | 1.8-11.8 % |
| form | liquid |
| grade | HPLC grade |
| impurities | ≤0.0005% non-volatile matter |
| ≤0.002% free acid (as CH3COOH) | |
| ≤0.05% peroxides (as H2O2) | |
| ≤0.05% water (Karl Fischer) | |
| InChI | 1S/C4H8O/c1-2-4-5-3-1/h1- |
| InChI key | WYURNTSHIVDZCO-UHFFFAOYSA |
| mp | −108 °C (lit.) |
| pH | ~7 |
| Quality Level | 100 ![]() |
| refractive index | n |
| SMILES string | C1CCOC1 |
| suitability | complies for IR spectroscopy |
| technique(s) | HPLC: suitable |
| UV absorption | λ: 245 nm Amax: ≤0.26 |
| λ: 275 nm Amax: ≤0.046 | |
| λ: 315 μm Amax: ≤0.0044 | |
| vapor density | 2.5 (vs air) |
| vapor pressure | 114 mmHg ( 15 °C) |
| 143 mmHg ( 20 °C) |
| Application: | Suitable for HPLC, spectrophotometry, environmental testing |
| Application: | Tetrahydrofuran may be used for the dissolution of poly-ε-caprolactone (PCL) and 1,3-diaminopentane, during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds and acrylate-terminated poly(5-amino-1-pentanol-c |
| General description: | Tetrahydrofuran (THF) is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THF forms a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1,4-diol is formed as an intermediate during the synthesis of THF. Hot THF is useful for the dissolution of polyvinylidene chloride (PVDV). |
| Other Notes: | Important notice • The article number 34865-4X2.5L will be discontinued. Please order the single bottle 34865-2.5L which is physically identical with the same exact specifications. • The article number 34865-6X1L will be discontinued. Please order the single bottle 34865-1L which is physically identical with the same exact specifications. |
| Other Notes: | Discover LiChropur reagents ideal for HPLC or LC-MS analysis |
| Packaging: | 1, 6×1, 2, 4×2.5, 4, 4×4 L in glass bottle |
| Packaging: | 100, 12×100 mL in glass bottle |
| Packaging: | 20 L in Nowpak™ |
| Packaging: | 200 L in Pure-Pac™ 1 |
| Packaging: | M-Bottle for Solvents As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before. See all the new features here! ![]() |
| Symbol | ![]() ![]() GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H319 - H335 - H336 - H351 |
| Precautionary statements | P201 - P202 - P210 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37-40 |
| Safety Statements | 13-16-29-33-36-37-46 |
| RIDADR | UN 2056 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | -6.2 °F - closed cup |
| Flash Point(C) | -21.2 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | ≥99.9% |
| bp | 65-67 °C (lit.) |
| mp | −108 °C (lit.) |
| Density | 0.889 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 41116105 |




