Acetic anhydride
SIGALD/33214 - puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99% (GC)
Synonym: Acetanhydride; Acetic acid anhydride; Acetyl acetate; Acetyl anhydride; Acetyl anhydride; Ethanoic anhydride
CAS Number: 108-24-7
Empirical Formula (Hill Notation): C4H6O3
Molecular Weight: 102.09
EC Number: 203-564-8
MDL Number: MFCD00008705
Linear Formula: (CH3CO)2O
Product Type: Chemical
| agency | reag. ISO |
| reag. Ph. Eur. | |
| USP/NF | |
| anion traces | chloride (Cl-): ≤2 mg/kg |
| phosphate (PO43-): ≤10 mg/kg | |
| sulfate (SO42-): ≤5 mg/kg | |
| assay | ≥99% (GC) |
| autoignition temp. | 629 °F |
| bp | 138-140 °C (lit.) |
| cation traces | Al: ≤0.5 mg/kg |
| B: ≤0.02 mg/kg | |
| Ba: ≤0.1 mg/kg | |
| Ca: ≤0.5 mg/kg | |
| Cd: ≤0.05 mg/kg | |
| Co: ≤0.02 mg/kg | |
| Cr: ≤0.05 mg/kg | |
| Cu: ≤0.02 mg/kg | |
| Fe: ≤0.1 mg/kg | |
| Mg: ≤0.1 mg/kg | |
| Mn: ≤0.02 mg/kg | |
| Ni: ≤0.02 mg/kg | |
| Pb: ≤0.1 mg/kg | |
| Sn: ≤0.1 mg/kg | |
| Zn: ≤0.2 mg/kg | |
| density | 1.08 g/mL (lit.) |
| expl. lim. | 10.3 % |
| grade | ACS reagent |
| puriss. p.a. | |
| impurities | ≤0.003% non-volatile matter |
| ≤0.01% KMnO4 red. matter (as O) | |
| InChI | 1S/C4H6O3/c1-3(5)7-4(2)6/ |
| InChI key | WFDIJRYMOXRFFG-UHFFFAOYSA |
| mp | −73 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | CC(=O)OC(C)=O |
| suitability | passes test for reaction against H2SO4 |
| vapor density | 3.5 (vs air) |
| vapor pressure | 10 mmHg ( 36 °C) |
| 4 mmHg ( 20 °C) |
| Application: | • Modification of Quinoa Starches: Acetic anhydride is used to modify the structure of starch molecules, discussing its implications on improving bread quality and food processing (Wang et al., 2024).  |
| General description: | Acetic anhydride is a colorless liquid. On dissolution in water, it undergoes solvolysis to afford acetic acid. It is widely employed as acetylation reagent for the acetylation of various alcohols. Wacher process (starting reagent + a ketene) and Knapsack process (starting reagent = acetaldehyde) have been reported for the industrial preparation of acetic anhydride. It is employed as solvent for various organic reactions. |
| Other Notes: | The article number 33214-4X2.5L will be discontinued. Please order the single bottle 33214-2.5L which is physically identical with the same exact specifications. The article number 33214-4X2.5L-M will be discontinued. Please order the single bottle 33214-2.5L-M which is physically identical with the same exact specifications. The article number 33214-6X1L will be discontinued. Please order the single bottle 33214-1L which is physically identical with the same exact specifications. The article number 33214-6X1L-M will be discontinued. Please order the single bottle 33214-1L-M which is physically identical with the same exact specifications. |
| Packaging: | 1, 6×1, 2.5, 4×2.5 L in poly bottle |
| Packaging: | 500 mL in poly bottle |
| Symbol |    GHS02,GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H226 - H302 - H314 - H330 |
| Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 10-20/22-34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 1715 3(8) / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 120.2 °F - closed cup |
| Flash Point(C) | 49 °C - closed cup |
| Supplemental Hazard Statements | EUH071 |
| Purity | ≥99% (GC) |
| bp | 138-140 °C (lit.) |
| mp | −73 °C (lit.) |
| Density | 1.08 g/mL (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |