Chloroform
SIGALD/319988 - contains ethanol as stabilizer, ACS reagent, ≥99.8%
Synonym: Methylidyne trichloride; Trichloromethane
CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 319988-1L.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 319988-500ML.
| assay | ≥99.8% |
| bp | 60.5-61.5 °C (lit.) |
| cation traces | Pb: ≤0.05 ppm |
| color | APHA: ≤10 |
| contains | ethanol as stabilizer |
| density | 1.48 g/mL at 25 °C |
| 1.492 g/mL at 25 °C (lit.) | |
| evapn. residue | ≤0.001% |
| form | liquid |
| grade | ACS reagent |
| impurities | Acetone and aldehyde, passes test |
| Acid and chloride, passes test | |
| Free chlorine (Cl), passes test | |
| H2SO4, passes test | |
| InChI | 1S/CHCl3/c2-1(3)4/h1H |
| InChI key | HEDRZPFGACZZDS-UHFFFAOYSA |
| mp | −63 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | ClC(Cl)Cl |
| vapor density | 4.1 (vs air) |
| vapor pressure | 160 mmHg ( 20 °C) |
| Application: | Chloroform can be used as a solvent in the:• Enzyme-catalyzed ring-opening polymerization of ω-pentadecalactone to prepare polyesters. • Pd-catalyzed cross-coupling reaction of acid chlorides with arylboronic acids to synthesize diaryl Ketones. • Enantio- and diastereoselective nitro-Mannich reaction of α-aryl nitromethanes with amido sulfones to synthesize β-nitroamines. • Diels-Alder reaction to synthesize spiro-fused dihydropyans. The hydrogen bond (CH-O) formed between chloroform and carbonyl oxygen makes the carbonyl group a stronger heterodienophile, resulting in an increased reaction rate. |
| General description: | Chloroform, a halogenated hydrocarbon, is widely used as a solvent and extractant in various manufacturing and laboratory procedures. It can be produced by the chlorination of methane or lower-chlorinated methanes. Additionally, it is employed in the production of dichlorocarbenes, α-trichloromethyl carbinols, and trichlorolithiocarbenoids |
| Packaging: | 1, 2.5, 4×4 L in glass bottle |
| Packaging: | 18, 200 L in steel drum |
| Packaging: | 500 mL in glass bottle |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
| Precautionary statements | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 63-20/22-36/38-40-48/20/22 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 1888 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| Purity | ≥99.8% |
| bp | 60.5-61.5 °C (lit.) |
| mp | −63 °C (lit.) |
| Density | 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12191502 |