Lithium chloride
SIGALD/310468 - ACS reagent, ≥99%
CAS Number: 7447-41-8
Empirical Formula (Hill Notation): ClLi
Molecular Weight: 42.39
EC Number: 231-212-3
MDL Number: MFCD00011078
Linear Formula: LiCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 310468-100G
This image depicts SKU: 310468-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 310468-500G
This image depicts SKU: 310468-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 310468-2.5KG
This image depicts SKU: 310468-2.5KG
| anion traces | sulfate (SO42-): ≤0.01% |
| assay | ≥99% |
| cation traces | Ba: ≤0.003% |
| Ca: ≤0.01% | |
| Fe: ≤0.001% | |
| heavy metals: ≤0.002% (by ICP) | |
| K: ≤0.01% | |
| Na: ≤0.20% | |
| form | crystalline powder |
| powder, crystals or granules | |
| grade | ACS reagent |
| impurities | ≤0.008 meq/g Titr. base |
| ≤0.01% insolubles | |
| InChI | 1S/ClH.Li/h1H;/q;+1/p-1 |
| InChI key | KWGKDLIKAYFUFQ-UHFFFAOYSA |
| loss | ≤1.0% loss on drying |
| mp | 605 °C (lit.) |
| pH | 6 |
| Quality Level | 200  |
| SMILES string | [Li+].[Cl-] |
| Application: | Lithium chloride can be used as: • A source of chloride anion for the conversion of alcohols to alkyl chloride under Mitsunobu conditions. • An additive in the palladium-catalyzed coupling and carbonylative coupling reactions of organostannanes and vinyl triflates. • A reagent for the cleavage of protecting groups under mild conditions. It readily converts acetals and ketals to the corresponding carbonyl compounds. • A reagent in the dehydrohalogenation of α-halocarbonyl compounds to α,β-unsaturated carbonyls compound in the presence of DMF. LiCl is also used with other reagents: • LiCl:DIPEA (1:1 molar ratio) is used in Horner–Wadsworth–Emmons alkenation reaction. • LiCl:Hexamethylphosphoric triamide is used in decarboxylative alkylation and chloride displacement reactions. • LiCl is used as an additive in solid-phase peptide synthesis because it increases resin swelling and improves the efficiencies of complex coupling steps. |
| Features and Benefits: | • Easy to handle • Weak Lewis acid • Highly soluble in water |
| General description: | Lithium chloride (LiCl) is a lithium salt. It is used as a source of chloride nucleophile as well as a source of chloride ligand in chemical synthesis. LiCl is also used as a desiccant in drying air streams. |
| Legal Information: | Redi-Dri is a trademark of Sigma-Aldrich Co. LLC |
| Other Notes: | Go to Redi-Dri™ Product Listing 746460 |
| Packaging: | 2.5 kg in poly bottle |
| Packaging: | 5, 100, 500 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H315 - H319 |
| Precautionary statements | P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | 605 °C (lit.) |
| UNSPSC | 12352302 |