Trifluoroacetic acid
SIGALD/299537 - ≥99%, for protein sequencing
Synonym: TFA
CAS Number: 76-05-1
Empirical Formula (Hill Notation): C2HF3O2
Molecular Weight: 114.02
EC Number: 200-929-3
MDL Number: MFCD00004169
Linear Formula: CF3COOH
Product Type: Chemical
| assay | ≥99% |
| bp | 72.4 °C (lit.) |
| density | 1.489 g/mL at 20 °C (lit.) |
| evapn. residue | <0.005% |
| form | liquid |
| impurities | <0.05% water |
| InChI | 1S/C2HF3O2/c3-2(4,5)1(6)7 |
| InChI key | DTQVDTLACAAQTR-UHFFFAOYSA |
| mp | −15.4 °C (lit.) |
| pH | 1 (20 °C, 10 g/L) |
| Quality Level | 100 ![]() |
| refractive index | n |
| SMILES string | OC(C(F)(F)F)=O |
| type | for protein sequencing |
| vapor density | 3.9 (vs air) |
| vapor pressure | 97.5 mmHg ( 20 °C) |
| Application: | Trifluoroacetic acid can be used as a solvent in the:• Mass spectrometry for protein identification. • Microwave-irradiated bromination of isoxazoles and pyrazoles with N-bromosuccinimide to synthesize mono-brominated isoxazoles and pyrazoles. • Lewis acid-catalyzed 6-endo-digcyclization of 2-(2-arylethynyl)heteroar • Electrospinning of cellulose acetate to prepare the corresponding nanofibrous membranes. |
| General description: | Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination. • High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues. • Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR. • Ensures Integrity of Genetic Material: Promotes reliable and reproducible results. • Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency. |
| General description: | Trifluoroacetic acid is a naturally occurring organic solvent and biodegradable by microbial action. It can also be used as a catalyst for various organic transformations, including solvolysis, rearrangements, reductions, oxidations, and trifluoromethylation. |
| Packaging: | 25, 100, 500 g in glass bottle |
| Symbol | ![]() GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H314 - H332 - H412 |
| Precautionary statements | P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 20-35-52/53 |
| Safety Statements | 9-26-27-28-45-61 |
| RIDADR | UN 2699 8 / PGI |
| WGK Germany | WGK 2 |
| Flash Point(F) | No data available |
| Flash Point(C) | No data available |
| Purity | ≥99% |
| bp | 72.4 °C (lit.) |
| mp | −15.4 °C (lit.) |
| Density | 1.489 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352106 |



