Osmium tetroxide solution
SIGALD/208868 - 2.5 wt. % in tert-butanol
CAS Number: 20816-12-0
Empirical Formula (Hill Notation): O4Os
Molecular Weight: 254.23
MDL Number: MFCD00011150
Linear Formula: OsO4
Product Type: Chemical
| concentration | 2.5 wt. % in tert-butanol |
| contains | tert-butyl hydroperoxide as stabilizer |
| density | 0.811 g/mL at 25 °C |
| 1.0 g/mL at 20 °C | |
| form | liquid |
| InChI | 1S/4O.Os |
| InChI key | VUVGYHUDAICLFK-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| reaction suitability | reagent type: oxidant |
| SMILES string | O=[Os](=O)(=O)=O |
| storage temp. | 2-8°C |
| vapor pressure | 5.42 psi ( 20 °C) |
| 6.76 psi ( 55 °C) |
| Application: | Osmium tetroxide solution is used as catalyst in the: • Cis dihydroxylation of alkenes to form cis-1,2-diols. • Direct oxidation of 1,4-dienes to yield carboxylic acids using oxone as a co-oxidant. Osmium tetroxide can also be used: • In the stereoselective synthesis of (+)-norrisolide. |
| General description: | Osmium tetroxide solution (OsO4) is commonly used as a catalyst in various organic reactions. OsO4 is a strong oxidizing agent and can be used to break carbon-carbon bonds. Additionally, it can be used in the cis dihydroxylation of alkenes, diastereoselective and asymmetric dihydroxylation, osmylation and oxyamination of alkenes. |
| Packaging: | 5, 25 mL in glass bottle |
| Symbol | ![]() ![]() ![]() GHS02,GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H311 + H331 - H315 - H318 - H335 - H336 - H341 |
| Precautionary statements | P210 - P280 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-36/37-43-68 |
| Safety Statements | 9-16-26-35-36/37-45 |
| RIDADR | UN 3286 8(6.1)(3) / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 39.2 °F - closed cup |
| Flash Point(C) | 4 °C - closed cup |
| Density | 1.0 g/mL at 20 °C; 0.811 g/mL at 25 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352303 |





