Tannic acid
SIGALD/16201 - puriss., powder
Synonym: Gallotannin; Tannin
CAS Number: 1401-55-4
Empirical Formula (Hill Notation): C76H52O46
Molecular Weight: 1701.20
EC Number: 215-753-2
MDL Number: MFCD00066397
Linear Formula: C76H52O46
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| autoignition temp. | 980 °F |
| form | powder |
| grade | puriss. |
| ign. residue | ≤0.1% (as SO4) |
| impurities | dextrines, gum matters, in accordance |
| resinous matters, in accordance | |
| InChI | 1S/C76H52O46/c77-32-1-22( |
| InChI key | LRBQNJMCXXYXIU-PPKXGCFTSA |
| loss | ≤9% loss on drying, 105 °C, 2 h |
| mp | 218 °C (lit.) |
| quality | meets analytical specification of USP |
| Quality Level | 200 ![]() |
| SMILES string | Oc1cc(cc(O)c1O)C(=O)Oc2cc |
| solubility | acetone: very soluble |
| alcohol: freely soluble (Diluted) | |
| alcohol: slightly soluble (Dehydrated) | |
| alcohol: very soluble | |
| benzene: insoluble | |
| carbon disulfide: insoluble | |
| carbon tetrachloride: insoluble | |
| chloroform: insoluble | |
| diethyl ether: insoluble | |
| glycerol: soluble 1gm in 1 ml (warm) | |
| H2O: soluble 1 gm in 0.35ml | |
| hexane: insoluble | |
| petroleum ether: insoluble |
| Application: | Tannic acid has been used: • as a reference standard to measure the total hydrolyzable tannins in Oak root bark tannin-methanol extract using a UV/Vis spectrophotometer • as a blood-brain barrier (BBB) impermeable, transcytosis-inhibiting drug in spheroid culture medium • as a flushing agent to test its effects on metal ions, total organic carbon, and organic matter of soil • as an inhibitor of free ovalbumin (OVA) uptake by the endocytic mechanism on dendritic cells |
| Biochem/physiol Actions: | Tannic acid has many pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, and anti-tumor effects. It also exerts anti-aging, wound healing, and neuroprotective activities. TA is traditionally used as a tanning agent in the food, leather, adhesive, and pharmaceutical industries. It is a natural crosslinker that is useful in building polymeric networks and can be used to design biomedical hydrogels. |
| General description: | Tannic acid is the simplest hydrolyzable tannin. The chemical structure of tannic acid has a glucose molecule in its core connected to 10 galloyls groups via aliphatic ester bonds. TA is one of the most abundant natural polyphenols, which can be colorless to yellow in color, and of astringent taste. It can be sourced from the bark of oak, chestnut, hemlock, mangrove, etc. |
| Packaging: | 100, 500 g in poly bottle |
| Risk Statements | 52/53 |
| Safety Statements | 61 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | 390.2 °F |
| Flash Point(C) | 199 °C |
| mp | 218 °C (lit.) |
| UNSPSC | 12352106 |

