Hydroxylamine hydrochloride
SIGALD/159417 - ReagentPlus®, 99%
Synonym: Hydroxylammonium chloride
CAS Number: 5470-11-1
Empirical Formula (Hill Notation): H3NO · HCl
Molecular Weight: 69.49
EC Number: 226-798-2
MDL Number: MFCD00051089
Linear Formula: NH2OH · HCl
Product Type: Chemical
| assay | 99% |
| density | 1.67 g/mL at 25 °C (lit.) |
| form | crystalline |
| InChI | 1S/ClH.H3NO/c;1-2/h1H;2H, |
| InChI key | WTDHULULXKLSOZ-UHFFFAOYSA |
| mp | 155-157 °C (dec.) (lit.) |
| pH | 2.5-3.5 (20 °C, 50 g/L) |
| product line | ReagentPlus® |
| Quality Level | 100 ![]() |
| SMILES string | Cl.NO |
| technique(s) | inhibition assay: suitable |
| vapor pressure | 0.001 hPa ( 50 °C) |
| Application: | Hydroxylamine hydrochloride can be used as a reactant: • in the synthesis of primary amides from aldehydes in the presence of cesium carbonate (Cs2CO3) as a catalyst. • in the conversion of alicyclic /aliphatic carbonyl compounds and the aromatic aldehydes into corresponding oximes. • in the one-pot synthesis of nitriles from aldehydes in the presence of sodium sulfate (anhyd) and sodium bicarbonate catalysts. • It can also be used as a reducing agent in the preparation of single-layer reduced graphene oxide (RGO) sheets and films. |
| Biochem/physiol Actions: | MAO inhibitor; inhibits platelet aggregation. |
| General description: | Hydroxylamine hydrochloride (Hydroxylammonium chloride) participates in the synthesis of 1,2,4-oxadiazoles, secondary amides and tertiary amides. |
| General description: | Hydroxylamine hydrochloride (NH2OH.HCl) is a hygroscopic salt widely used as a reactant in electrophilic substitution reactions, oxidation, and reduction reactions. It is also used in the synthesis of nitriles, pyrazoles, isox |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 100, 500 g in poly bottle |
| Packaging: | 3 kg in poly drum |
| Symbol | ![]() ![]() ![]() GHS05,GHS07,GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H290 - H302 + H312 - H315 - H317 - H319 - H351 - H373 - H400 |
| Precautionary statements | P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | E,Xn,N |
| Risk Statements | 2-21/22-36/38-40-43-48/22-50 |
| Safety Statements | 36/37-61 |
| RIDADR | UN2923 - class 8 - PG 3 - EHS - acidic - Corrosive solids, toxic |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99% |
| mp | 155-157 °C (dec.) (lit.) |
| Density | 1.67 g/mL at 25 °C (lit.) |
| UNSPSC | 12352300 |





