Glycerol
SIGALD/15523 - puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E422, anhydrous, 99.0-101.0% (alkalimetric)
Synonym: 1,2,3-Propanetriol; Glycerin
CAS Number: 56-81-5
Empirical Formula (Hill Notation): C3H8O3
Molecular Weight: 92.09
EC Number: 200-289-5
MDL Number: MFCD00004722
Linear Formula: HOCH2CH(OH)CH2OH
Product Type: Chemical
| anion traces | chloride (Cl-): ≤10 mg/kg |
| sulfate (SO42-): ≤10 mg/kg | |
| assay | 99.0-101.0% (alkalimetric) |
| 99.0-101.0% (calc. on H2O free substance) | |
| autoignition temp. | 698 °F |
| bp | 182 °C/20 mmHg (lit.) |
| cation traces | As: ≤1 mg/kg |
| Cu: ≤10 mg/kg | |
| Pb: ≤1 mg/kg | |
| Zn: ≤10 mg/kg | |
| density | ≥1.257 g/mL at 25 °C |
| 1.25 g/mL (lit.) | |
| 1.2580-1.2644 g/mL at 20 °C | |
| expl. lim. | 2.6-11.3 % |
| form | viscous liquid |
| grade | puriss. |
| ign. residue | ≤0.01% (as SO4) |
| impurities | acidity or alkalinity, complies |
| acrolein, glucose and NH4-compounds, complies | |
| aldehydes, in accordance | |
| ester, complies | |
| fatty acids and esters, complies | |
| impurities A and related substances (GC), complies | |
| residual solvents, complies | |
| sugar, complies | |
| ≤0.0005% heavy metals (as Pb) | |
| ≤0.003% free acid (as CH3COOH) | |
| ≤0.003% halogen compounds (as Cl) | |
| ≤0.2% 1,2,4-butantriole (GC) | |
| ≤2% water (Karl Fischer) | |
| InChI | 1S/C3H8O3/c4-1-3(6)2-5/h3 |
| InChI key | PEDCQBHIVMGVHV-UHFFFAOYSA |
| mp | 20 °C (lit.) |
| pH | 5.5-8 |
| quality | meets analytical specification of Ph. Eur., BP, USP, FCC, E422 |
| Quality Level | 200  |
| refractive index | n |
| n |
|
| SMILES string | OCC(O)CO |
| storage temp. | 15-25°C |
| suitability | complies for color |
| complies for reaction against H2SO4 | |
| corresponds for chromatography | |
| passes test for identity (IR) | |
| technique(s) | electrophoresis: suitable |
| IR spectroscopy: suitable | |
| vapor density | 3.1 (vs air) |
| vapor pressure | <1 mmHg ( 20 °C) |
| Application: | Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component. |
| Biochem/physiol Actions: | Glycerol has been used as • a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium. • a fuel during designing enzymatic biofuel cell. • a liquid composite matrix with 4-HCCA and 3-aminoquinoline for analysis of neutral and acidic glycans. • a matrix for fast atom bombardment MS. • may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis. |
| Biochem/physiol Actions: | Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release. |
| General description: | Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 390.2 °F - Pensky-Martens c |
| Flash Point(C) | 199 °C - Pensky-Martens clo |
| Purity | 99.0-101.0% (alkalimetric); 99.0-101.0% (calc. on H2O free substance) |
| bp | 182 °C/20 mmHg (lit.) |
| mp | 20 °C (lit.) |
| Density | 1.2580-1.2644 g/mL at 20 °C; ≥1.257 g/mL at 25 °C; 1.25 g/mL (lit.) |
| Refractive Index | n |
| Storage Temp. | 15-25°C |
| UNSPSC | 12352104 |