Berberine chloride
SIAL/Y0001149 - European Pharmacopoeia (EP) Reference Standard
Synonym: Berberine chloride form; Natural Yellow 18
CAS Number: 633-65-8
Empirical Formula (Hill Notation): C20H18ClNO4
Molecular Weight: 371.81
MDL Number: MFCD00011939
Linear Formula: C20H18ClNO4
Product Type: Chemical
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C20H18NO4.ClH/c1-22-17 |
| InChI key | VKJGBAJNNALVAV-UHFFFAOYSA |
| manufacturer/tradename | EDQM |
| SMILES string | COC1=C(C=[N+](CCC2=C3C=C4 |
| storage temp. | 2-8°C |
| Application: | Fluorescent stain for heparin in mast cells |
| Biochem/physiol Actions: | An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. |
| Caution: | Please find SDS provided by EDQM here.   . |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| Colour Index Number | 75160 |
| UNSPSC | 41116107 |