ProClin™ 950
SIAL/799130 - ProClin™ preservative for use in IVD manufacturing, pkg of 110 kg, MIT 9.5 %
Synonym: 9.5% solution of 2-
Product Type: Chemical
ProClin 950 attacks the central metabolic cycle of the cell, the Krebs cycle, at two specific enzymatic sites: succinate dehydrogenase and NADH dehydrogenase. Other inhibited enzymes include pyruvate dehydrogenase, which is vital for oxidation of pyruvate to acetyl-CoA; as well as lactate dehydrogenase and alcohol dehydrogenase, which detoxify waste byproducts synthesized during fermentation. With cellular metabolism debilitated, microorganisms rapidly lose their ability to produce ATP and carry on vital functions, such as transcription, translation and damage repair. All bacteria and fungi possess at least some parts of the Krebs cycle, thus ProClin 950 represents a highly efficient broad spectrum biocide.
| bp | 100 °C/1.013 hPa |
| color | colorless to light yellow |
| composition | MIT, 9.5% |
| density | 1.020 g/cm3 at 25 °C |
| form | liquid |
| matrix | Water |
| mp | -20--15 °C |
| operating pH range | 2-12 |
| packaging | pkg of 110 kg |
| parameter | <90 °C operating temperature |
| pH range | 3-6 |
| Quality Level | 300  |
| shelf life | 3 yr (from Date of Manufacture) |
| solubility | water: soluble at 20 °C |
| Application: | ProClin™ preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin™ highly efficient even over extended storage periods of your IVD components. |
| Disclaimer: | The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others. |
| Legal Information: | ProClin is a trademark of LANXESS Corp. |
| Packaging: | 110 kg in poly drum |
| Symbol |    GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H314 - H317 - H332 - H410 |
| Precautionary statements | P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| RIDADR | UN3265 - class 8 - PG 2 - EHS - Corrosive liquid, acidic, organi |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH071 |
| bp | 100 °C/1.013 hPa |
| mp | -20--15 °C |
| Density | 1.020 g/cm3 at 25 °C |
| UNSPSC | 12352201 |