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6-Maleimidohexanoic acid N-hydroxysuccinimide ester

SIAL/63177 - ≥98.0% (HPLC)

Synonym: 6-Maleimidocaproic acid N-succinimidyl ester; N-(ε-Maleimidocaproyloxy)succinimide; N-Succinimidyl 6-maleimidocaproate; EMCS

CAS Number: 55750-63-5
Empirical Formula (Hill Notation): C14H16N2O6
Molecular Weight: 308.29
MDL Number: MFCD00043043
Linear Formula: C14H16N2O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-63177-25MG 25 mg
 $227.00
1/EA		 Add To Favorites
45-63177-100MG 100 mg
 $0.00
1/EA
CALL FOR PRICE		 Add To Favorites

 

assay ≥98.0% (HPLC)
form solid
functional group NHS ester
InChI 1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI key VLARLSIGSPVYHX-UHFFFAOYSA-N
mp 67-73 °C
  70-73 °C (lit.)
Quality Level 200 
reaction suitability reagent type: linker
SMILES string O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
storage temp. −20°C
Application: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Other Notes: Reagent for cross-linking and immobilisation of proteins
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
Purity ≥98.0% (HPLC)
mp 67-73 °C; 70-73 °C (lit.)
Storage Temp. −20°C
UNSPSC 12352106

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