Sinapic acid
SIAL/49508 - matrix substance for MALDI-MS, ≥99.5%, Ultra pure
Synonym: 3,5-
CAS Number: 530-59-6
Empirical Formula (Hill Notation): C11H12O5
Molecular Weight: 224.21
EC Number: 208-487-3
MDL Number: MFCD00004401
Linear Formula: C11H12O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 49508-10MG-F
| analyte chemical class(es) | dendrimers, fullerenes, peptides, proteins |
| assay | ≥99.5% |
| ≥99.5% (HPLC) | |
| cation traces | Al: ≤1 mg/kg |
| Ba: ≤1 mg/kg | |
| Ca: ≤2 mg/kg | |
| Cd: ≤1 mg/kg | |
| Co: ≤1 mg/kg | |
| Cr: ≤1 mg/kg | |
| Cu: ≤1 mg/kg | |
| Fe: ≤1 mg/kg | |
| K: ≤2 mg/kg | |
| Li: ≤1 mg/kg | |
| Mg: ≤1 mg/kg | |
| Mn: ≤1 mg/kg | |
| Na: ≤2 mg/kg | |
| Ni: ≤1 mg/kg | |
| Sr: ≤1 mg/kg | |
| Zn: ≤1 mg/kg | |
| grade | matrix substance for MALDI-MS |
| InChI | 1S/C11H12O5/c1-15-8-5-7(3 |
| InChI key | PCMORTLOPMLEFB-ONEGZZNKSA |
| mp | ~202 °C |
| Quality Level | 100  |
| SMILES string | COc1cc(C=CC(O)=O)cc(OC) |
| solubility | dioxane: 1 g/10 mL at hot, clear, faintly yellow to yellow |
| suitability | in accordance for UV test |
| technique(s) | MALDI-MS: suitable |
| Biochem/physiol Actions: | On removal of amino group from phenylalanine, catalysing with enzyme phenylalanine ammonia-lyase forms cinnamic acid. The precursor of hydroxycinnamates is produced after hydroxylation of benzene ring. One of the precursors produced is sinapic acid. Sinapic acid exhibits antimicrobial, antioxidant, anticancer, anti-inflammatory, and anti-anxiety activity. Sinapine (sinapoyl choline) has been acknowledged as an acetylcholinesterase inhibitor, making it therapeutically applicable in treatment of various diseases. 4-Vinylsyringol (a decarboxylation product of sinapic acid) is a potent antimutagenic and antioxidative agent, involved in suppressing the induction of inflammatory cytokines and carcinogenesis. Owing to their anti-oxidative activity, these compounds have been considered to be potentially employed in the pharmaceutical industry, cosmetics and food processing. |
| Biochem/physiol Actions: | Sinapic acid was suitable as phenolic standard for HPLC analysis in determination of Sinapic acid derivatives in Canola extracts. 10 g/L of sinapinic acid with solvent was suitable as matrix for ultraviolet laser desorption mass spectrometric determination of proteins. It was also suitable to use as matrix for MALDI-TOFMS and MALDI-ion mobility-TOFMS to determine phospholipids in tissue. |
| General description: | Sinapic acid is one of the 4 most common hydroxycinnamic acids. It is widespread in the plant kingdom (vegetables, fruits, oilseed crops, cereal grains and medicinal plants, and some spices). It is mostly found in the form of esters, but may exist in the free form too. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.5% (HPLC); ≥99.5% |
| mp | ~202 °C |
| UNSPSC | 12000000 |