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Voriconazole

SIAL/32483 - VETRANAL®, analytical standard

Synonym: 2R,3S-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; UK-109496

CAS Number: 137234-62-9
Empirical Formula (Hill Notation): C16H14F3N5O
Molecular Weight: 349.31
MDL Number: MFCD00905717
Linear Formula: C16H14F3N5O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-32483-25MG 25 mg
 $155.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 32483-25MG

 

application(s) forensics and toxicology
pharmaceutical (small molecule)
format neat
grade analytical standard
InChI 1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1
InChI key BCEHBSKCWLPMDN-MGPLVRAMSA-N
product line VETRANAL®
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string C[C@@H](c1ncncc1F)[C@](O)(Cn2cncn2)c3ccc(F)cc3F
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions: It has been used as one of the constituent of YPD (1% yeast extract, 2% peptone, 2% glucose) liquid media.
Biochem/physiol Actions: Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.
Biochem/physiol Actions: Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-a sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.
Biochem/physiol Actions: Voriconazole is an antifungal, which inhibits ergosterol synthesis.
General description: Voriconazole is a second-generation triazole, and is derived from fluconazole. It has a broad and enhanced antifungal spectrum as compared to other older triazoles. It is mostly well tolerated and is available in both oral and intravenous formulations.
Legal Information: VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
UNSPSC 41116107

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