Bergamottin
SIAL/01338 - analytical standard
Synonym: Bergamotine; Bergaptin
CAS Number: 7380-40-7
Empirical Formula (Hill Notation): C21H22O4
Molecular Weight: 338.40
MDL Number: MFCD00017409
Linear Formula: C21H22O4
Product Type: Chemical
| application(s) | food and beverages |
| assay | ≥98.0% (HPLC) |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C21H22O4/c1-14(2)5-4-6 |
| InChI key | DBMJZOMNXBSRED-OQLLNIDSSA |
| mp | 75-80 °C |
| Quality Level | 100  |
| SMILES string | CC(C)=CCCC(C)=CCOc1c2 |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Bergamottin may be used as an analytical standard to test its efficacy in the following: • Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated. • Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products. |
| General description: | Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (HPLC) |
| mp | 75-80 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 85151701 |