Hyperoside
SIAL/00180585 - primary reference standard
Synonym: Quercetin 3-D-galactoside; 3,3′,4′,5,7-Pentahydroxyflavone 3-D-galactoside; Hyperin; Hyperoside
CAS Number: 482-36-0
Empirical Formula (Hill Notation): C21H20O12
Molecular Weight: 464.38
EC Number: 207-580-6
MDL Number: MFCD00016933
Linear Formula: C21H20O12
Product Type: Chemical
| grade | primary reference standard |
| InChI | 1S/C21H20O12/c22-6-13-15( |
| InChI key | OVSQVDMCBVZWGM-DTGCRPNFSA |
| manufacturer/tradename | HWI |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | OC[C@H]1O[C@@H](OC2=C(Oc3 |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | The primary reference standard can be used for identification, assay, and purity testing, method development, and validation. It can also be used as follows: • Development of an ultra performance liquid chromatography-mass spectrometric method to determine hyperoside in rat plasma samples following sample treatment by protein precipitation and liquid-liquid extraction • Multi-residue analysis of hyperoside, isoquercitrin, and eleutheroside E in botanical samples of Apocynum venetum L. and Eleutherococcus senticosus used in traditional Chinese medicine by HPLC combined with diode array detection (DAD) • Ionic liquid vacuum microwave-assisted extraction (ILVMAE) of rutin, hyperoside, and hesperidin from Sorbus tianschanica leaf samples for their subsequent quantification by HPLC • Simultaneous detection and quantification of vitexin, rutin, hyperoside, and quercetin in hawthorn flower and leaf extract samples using high-performance liquid chromatography combined with spectrophotometric detection (HPLC-UV) |
| Biochem/physiol Actions: | Protects against peroxide-induced oxidative damage to cells by scavenging reactive oxygen species and enhancing activity of anti-oxidant enzymes, in particular, catalase and glutathione peroxidase. |
| General description: | Hyperoside is a flavonol glycoside compound used in Traditional Chinese medicine for its various beneficial effects, such as anti-inflammatory, anti-oxidant, anti-viral, and anti-cancer. |
| General description: | Produced and qualified by HWI pharma services GmbH. Exact content measured by quantitative NMR can be found on the certificate. |
| Other Notes: | A flavonol glycoside widely distribute in plants, including mimosa and St. John′s wort. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 85151701 |