Plasmin, human
ROCHE/10602361001 - from human plasma
Synonym: Plasmin
Product Type: Chemical
| assay | 95% (electrophoresis) |
| biological source | human plasma |
| form | suspension |
| manufacturer/tradename | Roche |
| mol wt | Mr ~85 kDa |
| optimum pH | 8.9 |
| packaging | pkg of 0.5 mL (5 U) |
| Quality Level | 100  |
| shipped in | wet ice |
| specific activity | ~8 units/mg protein (At 25 °C with Chromozym PL as the substrate.) |
| Application: | Human plasmin has been used as an oligopeptide substrate in peptidase inhibition assays. |
| Biochem/physiol Actions: | Plasmin is a direct acting fibrinolytic enzyme present in blood. Its activity is independent of plasminogen presence during fibrinolysis. Plasmin is rapidly and irreversibly inhibited by α-2 antiplasmin. |
| General description: | Inhibitors: DFP, PMSF, TLCK, leupeptin, aprotinin, soybean trypsin inhibitor, α1-antitrypsin, α2-macroglobulin, anti-thrombin III heparin, APMSF, and α2-antiplasmin |
| General description: | Fibrinolysin |
| Other Notes: | For life science research only. Not for use in diagnostic procedures. |
| Physical form: | Suspension in 3.2 M ammonium sulfate solution |
| Preparation Note: | Stabilizers: Human plasmin does not contain stabilizers. Storage conditions (working solution): 2 to 8 °C Diluted solution (pH 8.6) is stable at 2 to 8 °C for at least 1–2 weeks. For storage of dialyzed solution freezing in aliquots is recommended. |
| Specificity: | Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin. |
| Storage and Stability: | Store at 2 to 8 °C. (Recommended form for storage is ammonium sulfate suspension 3.2 M, pH 8.6.) |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | No data available |
| Flash Point(C) | No data available |
| Purity | 95% (electrophoresis) |
| activity | specific activity: ~8 units/mg protein (At 25 °C with Chromozym PL as the substrate.) |
| Enzyme Commission (EC) Number | 3.4.21.7 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |