Glucose-6-phosphate
ROCHE/10127647001 - mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g
Synonym: D-Glucose 6-phosphate disodium salt hydrate; G-6-P-Na2; Robison ester
CAS Number: 3671-99-6
Empirical Formula (Hill Notation): C6H11Na2O9P · xH2O
Molecular Weight: 304.10 (anhydrous basis)
MDL Number: MFCD00150940
Linear Formula: C6H11Na2O9P · xH2O
Product Type: Chemical
| form | solid |
| InChI | 1S/C6H13O9P.2Na.H2O/c7-3- |
| InChI key | UUWJZXLTPORJKW-WYFATIGWSA |
| manufacturer/tradename | Roche |
| mol wt | (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2) |
| packaging | pkg of 5 g |
| shipped in | ambient |
| SMILES string | O.[Na+].[Na+].OC1O[C@H](C |
| Application: | Substrate for glucose-6-phosphatase. |
| Biochem/physiol Actions: | In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase. |
| Components: | 77% glucose-6-P (enzymatic), 13% sodium, 8% water |
| Formula variant: | C6H11O9PNa2 |
| General description: | Disodium salt |
| Other Notes: | For life science research only. Not for use in diagnostic procedures. |
| Quality: | Contaminants: <0.2% glucose (enzymatic) |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| UNSPSC | 12352200 |