N,N-Dimethylformamide
ALDRICH/L091000
Synonym: DMF; NSC 5356
CAS Number: 68-12-2
Empirical Formula (Hill Notation): C3H7NO
Molecular Weight: 73.09
EC Number: 200-679-5
MDL Number: MFCD00003284
Linear Formula: HCON(CH3)2
Product Type: Chemical
| autoignition temp. | 833 °F |
| bp | 153 °C (lit.) |
| color | clear |
| density | 0.944 g/mL (lit.) |
| expl. lim. | 15.2 % |
| form | liquid |
| impurities | ≤200 ppm water content (Karl Fischer) |
| ≤9 ppm Amine content | |
| InChI | 1S/C3H7NO/c1-4(2)3-5/h3H, |
| InChI key | ZMXDDKWLCZADIW-UHFFFAOYSA |
| mp | −61 °C (lit.) |
| pH | 6.7 |
| product line | Proligo Reagents |
| Quality Level | 100 ![]() |
| refractive index | n |
| SMILES string | [H]C(=O)N(C)C |
| storage condition | dry at room temperature |
| type | for DNA synthesis |
| vapor density | 2.5 (vs air) |
| vapor pressure | 2.7 mmHg ( 20 °C) |
| Application: | DMF is a widely used polar solvent in which organic, organometallic, and bioorganic transformations are carried out. It is also a solvent for many hydrophobic organic compounds and acts as a source of building blocks in various organic synthesis reactions. |
| Application: | Solvent for many hydrophobic organic compounds. |
| General description: | N,N-Dimethylformamide (DMF) is an amide that works as a multipurpose reagent that is an effective polar solvent for various compounds and a ligand for metallic compounds. It also acts as a key intermediate as an electrophilic or nucleophilic agent for mediating reactions as it delivers its own H, C, N, and O atoms in compound synthesis. |
| Symbol | ![]() ![]() GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H226 - H312 + H332 - H319 - H360D |
| Precautionary statements | P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-20/21-36 |
| Safety Statements | 53-45 |
| RIDADR | UN 2265 3 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 135.5 °F - closed cup |
| Flash Point(C) | 57.5 °C - closed cup |
| bp | 153 °C (lit.) |
| mp | −61 °C (lit.) |
| Density | 0.944 g/mL (lit.) |
| Refractive Index | n |
| UNSPSC | 12352111 |




