Cap A
ALDRICH/L040082
Product Type: Custom product
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| product line | Proligo Reagents |
| Quality Level | 200  |
| type | for DNA synthesis |
| Other Notes: | Cap A solution, containing acetic anhydride and tetrahydrofuran (THF), is used after the phosphoramidite reaction/coupling step. This solution aborts chains bearing unreacted 5′hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps. |
| Preparation Note: | Acetic Anhydride / Tetrahydrofurane 9.1/90.9 (v/v) |
| Symbol |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 + H332 - H315 - H318 - H335 - H336 - H351 |
| Precautionary statements | P210 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-37/38-40-41 |
| Safety Statements | 16-26-36/37/39 |
| RIDADR | UN 2056 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 6.1 °F |
| Flash Point(C) | -14.4 °C |
| Supplemental Hazard Statements | EUH019 - EUH071 |
| UNSPSC | 12352200 |