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BTT Activator

ALDRICH/L033000 - 0.3 M

Synonym: 5-(Benzylthio)-1H-tetrazole solution

CAS Number: 21871-47-6
Empirical Formula (Hill Notation): C8H8N4S
Molecular Weight: 192.24
MDL Number: MFCD00068731
Linear Formula: C8H8N4S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-L033000-4X2.5L 2.5 L
 $2130.00
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color clear
concentration 51.9-63.4 g/L (BTT content, titration)
InChI 1S/C8H8N4S/c1-2-4-7(5-3-1)6-13-8-9-11-12-10-8/h1-5H,6H2,(H,9,10,11,12)
InChI key GXGKKIPUFAHZIZ-UHFFFAOYSA-N
product line Proligo Reagents
Quality Level 200 
SMILES string C(Sc1nnn[nH]1)c2ccccc2
storage condition dry at room temperature
type for DNA synthesis
General description: Activator solution, containing powerful activators like 4,5-dicyanoimidazole(DCI), 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) or5-(Ethylthio)-1H-tetrazole (ETT) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step. The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.BTT Activator 0.3M is 5-(Benzylthio)-1H-tetrazole.
Preparation Note: Acetonitrile / 5-(Benzylthio)-1H-Tetrazole 100 / 6 (v/w)
UNSPSC 12352100

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