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Activator 42®

ALDRICH/L031000 - 0.1 M

Synonym: 5-[3,5-Bis(trifluoromethyl)phenyl]-1H-tetrazole Solution; 5-[3,5-Bis(trifluoromethyl)phenyl]-2H-tetrazole Solution; Activator 42® Solution

CAS Number: 175205-09-1
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-L031000-6X450ML 450 mL
$558.00
6/EA
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

color clear
concentration 28-31 g/L (Activator 42 content, titration)
impurities ≤30 ppm water content (Karl Fischer)
InChI 1S/C9H4F6N4/c10-8(11,12)5-1-4(7-16-18-19-17-7)2-6(3-5)9(13,14)15/h1-3H,(H,16,17,18,19)
InChI key KKJFZIQEWZVVIV-UHFFFAOYSA-N
product line Proligo Reagents
Quality Level 200 
SMILES string FC(F)(F)c1cc(cc(c1)c2n[nH]nn2)C(F)(F)F
storage condition dry at room temperature
type for DNA synthesis
Legal Information: Activator 42 is a registered trademark of Sigma-Aldrich Co. LLC
Legal Information: This product and it use is are covered under US Patent Number 7,897,758
Other Notes: Activator solution, containing 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.
Preparation Note: Acetonitrile / Activator 42 100 / 3 (v/w)
UNSPSC 41106305

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