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ETT Activator

ALDRICH/L030004 - 0.25M

Synonym: 5-(Ethylthio)-1H-tetrazole; 5-(Ethylthio)tetrazole solution

MDL Number: MFCD00068733
Product Type: Custom product

Catalog Number PKG Qty. Price Quantity
45-L030004-200L 200 L
$11130.00
1/EA
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concentration 32-35 g/L (titration)
form liquid
impurities ≤30 ppm water content (Karl Fischer)
InChI 1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)
InChI key GONFBOIJNUKKST-UHFFFAOYSA-N
product line Proligo Reagents
Quality Level 200 
SMILES string CCSc1nnn[nH]1
type for DNA synthesis
Other Notes: Activator solution, containing 5-(Ethylthio)-1H- tetrazole (ETT) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.
Preparation Note: Acetonitrile / 5-(Ethylthio)-1H-Tetrazole 100 / 3 (v/w)
UNSPSC 41116105

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