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18α-Glycyrrhetinic acid

ALDRICH/G8503 - ≥95%

Synonym: 18α-Glycyrrhetic acid; 18-Isoglycyrrhetinic acid; 3β-Hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid

CAS Number: 1449-05-4
Empirical Formula (Hill Notation): C30H46O4
Molecular Weight: 470.68
EC Number: 215-907-9
MDL Number: MFCD00064897; MFCD00064897
Linear Formula: C30H46O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G8503-250MG 250 mg
 $126.00
1/EA		 Add To Favorites
45-G8503-1G 1 g
 $466.00
1/EA		 Add To Favorites

 

assay ≥95%
InChI 1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21+,22+,23-,26-,27+,28+,29-,30-/m1/s1
InChI key MPDGHEJMBKOTSU-PMTKVOBESA-N
Quality Level 100 
SMILES string [H][C@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)C4[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O
Application: 18α-Glycyrrhetinic acid may be used to synthesize:
• 3-keto-18α-glycyrrhetinic acid
• methyl esters of 18α-glycyrrhetinic acid
• methyl esters of 3-keto-18α-glycyrrhetinic acid
General description: 18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1). It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).
Packaging: 1 g in poly bottle
Packaging: 250 mg in poly bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95%
UNSPSC 12352115

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