Guanine
ALDRICH/G11950 - 98%
Synonym: 2-
CAS Number: 73-40-5
Empirical Formula (Hill Notation): C5H5N5O
Molecular Weight: 151.13
EC Number: 200-799-8
MDL Number: MFCD00071533
Linear Formula: C5H5N5O
Product Type: Chemical
| assay | 98% |
| InChI | 1S/C5H5N5O/c6-5-9-3-2(4(1 |
| InChI key | UYTPUPDQBNUYGX-UHFFFAOYSA |
| mp | >300 °C (lit.) |
| Quality Level | 200  |
| SMILES string | NC1=Nc2[nH]cnc2C(=O)N1 |
| solubility | hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green |
| Application: | Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers. |
| General description: | Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine. |
| Packaging: | 10, 25, 100 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 98% |
| mp | >300 °C (lit.) |
| UNSPSC | 12352005 |