Chrysin
ALDRICH/C80105 - ≥96.5%
Synonym: 5,7-Dihydroxyflavone
CAS Number: 480-40-0
Empirical Formula (Hill Notation): C15H10O4
Molecular Weight: 254.24
EC Number: 207-549-7
MDL Number: MFCD00006834
Linear Formula: C15H10O4
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C80105-25G
| λmax | 348 nm |
| application(s) | diagnostic assay manufacturing hematology histology |
| assay | ≥96.5% |
| color | beige |
| form | powder |
| InChI | 1S/C15H10O4/c16-10-6-11(1 |
| InChI key | RTIXKCRFFJGDFG-UHFFFAOYSA |
| mp | 284-286 °C (lit.) |
| Quality Level | 100  |
| SMILES string | Oc1cc(O)c2C(=O)C=C(Oc2c1) |
| solubility | 0.1 M NaOH: 0.008 g/L |
| storage temp. | room temp |
| Application: | • Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli. • It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line. • It has been used to study the effect of chrysin on human ovarian cancer cells. |
| Biochem/physiol Actions: | Chrysin is a flavonoid and an analog of apigenin. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in models with latent infection. Chrysin exhibits anti-inflammatory and anti-oxidant effects. This molecule induces apoptosis in various cells, thereby exhibiting cancer chemopreventive activity. Chrysin can modulate the activity of GABAA (Type-A γ-aminobutyric acid) and GABAC receptors, it downregulates expression of PCNA (proliferating cell nuclear antigen), reduces activity of CDK2 (cyclin-dependent kinase 2) and CDK4 and induces p38-MAPK (mitogen-activated protein kinase) activation. |
| Packaging: | 25 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥96.5% |
| mp | 284-286 °C (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12171500 |